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Data from three randomized studies in healthy adult subjects receiving single doses of either Armodafinil (50, 100, 200, 250, 300 or 400 mg) or modafinil (400 mg) were pooled, and subsequently dose-normalized to a 200 mg dose for each drug. Subjects received 4 weeks of both Armodafinil (150-250 mg) and placebo with order randomized.

Other names for this medication:
Armodafinil, Waklert, Armod, Nuvigil,

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Armodafinil comes as a tablet to take by mouth. It is usually taken once a day. If you are taking armodafinil to treat narcolepsy or OSAHS, you will probably take it in the morning. If you are taking armodafinil to treat shift work sleep disorder, you will probably take it 1 hour before the start of your shift. Take armodafinil at around the same time every day. Do not change the time of day that you take armodafinil without talking to your doctor. Talk to your doctor if your work shift does not begin at the same time every day. Follow the directions on your prescription label carefully, and ask our doctor or pharmacist to explain any part you do not understand. Take armodafinil exactly as directed.

Armodafinil may be habit forming. Do not take a larger dose, take it more often, or take it for a longer period of time than prescribed by your doctor.

Armodafinil may decrease your sleepiness, but it will not cure your sleep disorder. Continue to take armodafinil even if you feel well-rested. Do not stop taking armodafinil without talking to your doctor.

Armodafinil should not be used in place of getting enough sleep. Follow your doctor's advice about good sleep habits. Continue to use any breathing devices or other treatments that your doctor has prescribed to treat your condition, especially if you have OSAHS.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

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Although the current models appear to be more accurate than the models submitted to the CASP meeting in 1994, the four major types of errors in side chain packing, position and conformation of aligned segments, position and conformation of inserted segments, and in alignment still occur to almost the same degree. Advances in knowledge: This is the first study to show the beneficial effect of traction during standard non-arthrography MRI of the wrist and compare the effect of traction between non-arthrographic and arthrographic MRI of the wrist. Ten participants (5 males and 5 females) completed each group fitness class in random order with energy expenditure and heart rate determined using an Actiheart monitor. We identified BcSUN1 as the only member of the Group-I SUN family of proteins encoded in the B.

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Northern (RNA) blot analyses detected an 800-nucleotide RNA specific to the csgA gene and a 900-nucleotide RNA specific to the fprA gene. A total of 262 consecutive patients with a diagnosis of TA between January 2009 and July 2013 were included in this study. To assess knowledge about calcium and dietary intake among a sample of adolescents. p53, vessel count, and vascular endothelial growth factor expression in human colon cancer.

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Various autacoids, including the eicosanoids, platelet activating factor (PAF) and bradykinin, have been implicated in the pathogenesis of sepsis and septic shock. Delayed presentation or large leakage of bowel content into the peritoneal cavity and the attendant ease with which peritonitis develops in the latter are factors responsible.

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With limited response rate and potential toxicity to chemotherapeutic treatment in patients with recurrent glioma, reliable response assessment is essential. Our results show that the hemifield visual stimulation only activates LGN in the contralateral hemisphere, and the lower-field and upper-field visual stimulations activate the superior and inferior portion of LGN, respectively. This study aimed to determine how vertebral fracture and vertebroplasty affect compressive load-sharing and vertebral deformations at adjacent spinal levels. We found that the new one-time method provided faster and more convenient central catheterization and catheter securement than the conventional methods. The purpose of this study was to analyze the CT contrast enhancement washout curves of adrenal masses and to determine the earliest time after initial enhancement that differentiation of adenomas from nonadenomas is possible.

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Structure of the chicken interferon-gamma gene, and comparison to mammalian homologues. This disease seems very uncommon but its frequency is perhaps underestimated in Africa. We report the first case described of septic arthritis caused by Absidia corymbifera in the setting of cellular immune deficiency associated with HIV-1 infection. While the service was not initially planned as an integrated approach to child health, its evolution reflects the move to more community based care delivery and the expansion of nurse-led initiatives in New Zealand.

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In untreated microsomes the energies of activation for the processes of decay were different for glucose-6-phosphatase and mannose-6-phosphatase activities, suggesting that the rate-limiting steps for the hydrolysis of these compounds were different. Only randomised, multicentre therapeutic trials in comparable groups of patients can provide information about the effects of medical treatment on the long-term prognosis of cardiac failure. The histological changes were observed with the use of HE staining, and the protein expression of VEGF, FLK-1 were measured by immunohistochemical test. These regions were then identified by peptic proteolysis, fast microbore high-performance liquid chromatography separation, and electrospray ionization mass spectrometry. The specificity of the lectins used, and the sensitivity of the detection system, provide valuable conclusions on the glycan structures.

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Twenty-one patients with primary hyperparathyroidism were examined prospectively. We conclude that hyperbilirubinemia per se, even in the concentration range where phototherapy is not currently recommended, can give rise to alterations in neonatal behavior. We identified missense mutations (C105Y, A199V, and R298H) in FTLD cases with family history and/or with low plasma PGRN levels.

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Digital reconstruction is a reliable method to correct for different projection angles and to monitor the effects of orthodontic movement in serial dental radiographs. Binding was efficient with different concentrations of cells, different cytokine concentrations and after the incubation in simulated gastric juice. Translational regulation of the expression of ribosomal protein genes in Xenopus laevis. Here, we present a unique case with AIH-PSC overlap syndrome and innumerable liver masses.

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Despite the fact that the visceral yolk sac is composed of endoderm and mesoderm, the tissues in the resulting tumor obtained from the ectopically implanted yolk sac showed derivatives from all three germ layers, including skin, bone, gut and nervous tissues. In contrast to IFN gamma production, IFN alpha/beta production by Newcastle disease virus (NDV)-infected mouse and human lymphocytes or fibroblasts was not inhibited by the addition of CsA (1 microgram/ml).

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The annually recurrent spring phytoplankton blooms in freshwater lakes initiate pronounced successions of planktonic ciliate species. We present two patients who were given trials of TENS for different chronic pain complaints.

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Internal validity was assessed independently by two referees with a detailed checklist for sources of bias. Isothiazolinones (MCI/MI): 200 ppm versus 100 ppm in the standard series. Cse4, the CENP-A homologue from Saccharomyces cerevisiae, is methylated on arginine 37 in its N-terminus (R37), and the absence of methylation (cse4-R37A) causes synthetic genetic defects in combination with mutations or deletions in genes encoding components of the Ctf19/CCAN complex and with the CDEI binding protein Cbf1. Influence of aflatoxin B1 on gas production by lactic acid bacteria.

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Our observation suggests that the evidence of Pseudotumor in case of small-head metal-on-metal arthroplasty should be considered with the same properties of big-head and therefore these patients should be followed scrupulously. A 68-year-old female patient was radiologically diagnosed with coin lesion in the lower right lobe. Patient was started on dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin and rituximab (EPOCH-R) with complete response to treatment.

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Thus, the active synthesis of sugars in shoots was essential to the development of salt tolerance. These procedures are illustrated with a radioimmunological study of the cross-reactivity of a desipramine-elicited monoclonal antibody with other tricyclic antidepressants. However, cotreatment with carbenoxolone (Cbx) and phosatidylinositol 3-kinase (PI3K) inhibitor LY 294002 to a focal cerebral ischemia and reperfusion rat model has not been studied yet. We thus amplify the previously described polarity of chimeric TB peptides that raise antibodies mainly against their C-terminal part.

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The electron-dense material, thought to be the peptide, was found in the sarcoplasmic reticulum, and it is suggested that a secretory pathway of the peptide through the latter to extracellular space, may be present, in addition to an exocytotic one. Furthermore, activin administration caused acute thermal hyperalgesia in wild-type mice, but not in TRPV1-null mice.

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Specific bronchial provocation tests with flour in the diagnosis of occupational bronchial asthma Restenosis of the CYPHER-Select, TAXUS-Express, and Polyzene-F nanocoated cobalt-chromium stents in the minipig coronary artery model. The APP Intracellular Domain Is Required for Normal Synaptic Morphology, Synaptic Plasticity, and Hippocampus-Dependent Behavior. Glycosylation at threonines 48 and 71 of human proBNP contributed to the increased secretion of proBNP by attenuating its processing, and GalNAc-transferase (GALNT) 1 and 2 mediated the glycosylation-regulated increase in cardiac human proBNP secretion.

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Spodoptera frugiperda cell line Sf9 was most sensitive, whereas Spodoptera exigua cell lines SeUCR and SelZD2109 showed intermediate sensitivity. The active components of the plant have no antifungal effect on the tested yeast (Candida albicans).

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The UF-qPCR assay performance, including recovery rate, linearity, detection sensitivity, precision and diagnostic accuracy that compared to the CAP-CTM V2.0 assay by analyzing batched low viral load clinical samples was evaluated. Age-related changes in serum undercarboxylated osteocalcin and its relationships with bone density, bone quality, and hip fracture. Height and weight were converted to body mass index (BMI) percentile-for-age scores.

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Our results indicated that both the monoclonal and polyclonal antibodies established in this study were highly specific for I-FABP, but not for L-FABP and H-FABP. Consecutive patients with primary diagnosis of AF who qualified for first-ever catheter ablation between 2011 and 2013 were enrolled.

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Novel infrared vibron absorption in solid hydrogen at megabar pressures. Two different observers evaluated the slides and the intensities of 32 histologic parameters were graded on a four-point scale to minimize the subjective variability in the histologic reports. To show that glomerular filtration rate (GFR) and bladder capacity (BC) develop isometrically, and to provide graphs for estimating GFR and BC for specific individuals of any age, sex, height and weight, for cystometric purposes. In view of the fact that in prognosis and treatment of arterial occlusion, particular importance must be attached to the profunda femoris artery, and especially to the region of origin of this artery, it is imperative to achieve angiographic representation of the descent of the profunda femoris artery without any masking.

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Chemotactic factor activity preceded the observed increase of polymorphonuclear cells in bronchoalveolar lavage fluids, suggesting a role for chemotactic factors in the sequestration of these cells in the lung. It is important that other causes of sinus tachycardia are excluded before making a diagnosis.

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Mutant of Escherichia coli K-12 with defective phosphorylation of two periplasmic transport proteins. In addition to whole organs, the transplantation of cells and tissues with specific differentiated functions represents an important conceptual and medical advance. Orthodromic stimulation of climbing fiber afferents evoked similar excitatory synaptic responses (complex spikes) in Purkinje neurons of both transgenic and control mice. Ovarian tissue cryopreservation and transplantation: banking reproductive potential for the future.

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In this article, we will discuss these novel therapeutic agents and currently available data in SCLC. In 1995, in order to improve the quality of this work, Norwegian paediatricians established a peer review group which meets on a regular basis.

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Neuropeptides may be used to stimulate or inhibit neurocircuitry involved in regulation of visceral organ function, including glucose metabolism. Iodoacetic acid inhibited wild-type enzyme activity in a time- and pH-dependent manner but did not affect the already reduced activity of mutant C82A. We have reexamined the phylogeny of the ciliates using alpha-tubulin and phosphoglycerate kinase gene sequences. It is known from our previous studies that kiwifruits, which are used in common human diet, have preventive properties of coronary artery disease. A condition of cerebrovascular instability on the arteriolar level probably was induced by the examination procedure.

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Conclusions Dengue in Sri Lanka is receiving increasing media attention. Key questions for future research to further delineate the health effects of weight stigmatization are summarized. Immunoactive inhibin as a marker of Sertoli cell function following cytotoxic damage to the human testis. Limited data exists on patients receiving therapeutic hypothermia during extracorporeal life support (ECLS). berghei speed up significantly comparing with the mice infected with the N strain.

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Earlier work showed that the biodegradation of a commercial linear monoalkyldiphenyletherdisulfonate surfactant as a carbon source for microbial growth leads to the quantitative formation of corresponding disulfodiphenylether carboxylates (DSDPECs), which were not degraded. Minimally invasive spine surgery (MISS) has been increasingly advocated during the last decade with new studies being reported every year. Orbital atherectomy for treating de novo, severely calcified coronary lesions: 3-year results of the pivotal ORBIT II trial.

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This paper reports the preparation of methyl substituted all-cis tetrafluorocyclohexanes prepared from a Birch reduction of benzoic acid, worked up with a methyl iodide quench. Here we show that RECQ1 is significantly overexpressed in MMCs compared to normal plasma cells and that increased RECQ1 expression is associated with poor prognosis in three independent cohorts of patients. There was also evidence suggesting that the large HDAg could be copackaged into the HBsAg particles, without the presence of the HDV genome and the small HDAg. Results obtained on a 7T preclinical MR scanner indicate that the low velocities in the heterogeneous system can be correctly quantified with high spatial resolution and an adequate total measurement time, enabling future studies on flow during the filtration process. Vascular endothelial cells with senescence-associated phenotypes are present in human atherosclerotic lesions, and endothelial cell senescence induced by telomere shortening may contribute to atherogenesis.

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Due to advances in scientific technology, endoscopic treatment of gastrointestinal submucosal tumors has become increasingly popular. Energy sources for HCO3- and CO2 transport in air-grown cells of synechococcus UTEX 625 Emodin, physcion and chrysophanol were isolated from the Evodia for the first time.

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Preoperative chemotherapy and radiation therapy in the management of anal epidermoid carcinoma. Overlap between irritable bowel syndrome and functional dyspepsia including subtype analyses. The consequences for isolation, identification and clinical potential are described.

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One such originally non-groupable isolate showed a weak agglutination reaction specifically with group B antiserum when reexamined. R-spondin is a secreted molecule that activates Wnt/beta-catenin signaling. Application of Q10-containing formulas significantly increased the levels of this quinone on the skin surface.

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Both, the relative weak posterior structures and the position of adduction, may explain the posterior subluxation observed in one of our specimens. A total of four phantoms (two male and two female) with eight defects (four locations and two sizes) were generated and projection data were simulated using an analytical projector with attenuation, scatter, collimator response and acquisition orbit modelling. Exact distribution of eigenvalue curvatures of chaotic quantum systems.

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Treatment options include dexamethasone, as well as the off-label use of metformin. The goal of this work was to better understand speech perception for cochlear implant (CI) users with bilateral residual hearing, including consideration of effects related to listening conditions and test measures. The literature on the clinical features and the response to chemotherapy of primary plasma cell leukemia is reviewed. Far-infrared reflectance spectra of Si:P near the metal-insulator transition.

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We conclude that there is a species difference in the subcellular distribution of this important steroidogenic enzyme and that this species difference may be related to the steroidogenic pathway preferred in that species. Heating for the full cook time of 28 min, however, resulted in a mean measured temperature of 85 degrees C and no surviving listerias were detected.

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Deregulations in the NF-kappaB pathway could be part of the mechanism responsible for the muscle wasting resulting from CAPN3 deficiency. There are now 11 genes that satisfy these conditions and thus have been shown to be crucial for metanephric kidney development: WT-1, Pax-2, c-ret, GDNF, alpha8beta1, Wnt-4, BF-2, BMP-7, PDGF B, PDGFRbeta, and alpha3beta1. Clinical characteristics, treatments, recurrence, and prognosis were analyzed. This phenotype of FHS is likely to represent a more severe form of FHS. Psychiatric Comorbidity, Social Aspects and Quality of Life in a Population-Based Cohort of Expecting Fathers with Epilepsy.

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The double-regulatory effects of monomer T4 might be important for evaluation of the therapeutic effects of Tripterygium wilfordii Hook in future clinical practice. Cell growth inhibition was associated with down-regulation of extracellular signal-regulated kinase 1/2 activity, with increased levels of the cell-cycle inhibitor p27(kip1) protein and with dephosphorylation of PLCgamma1, a substrate of DEP-1, the human homologue of r-PTPeta. Given this, we investigated and compared photosynthetic characteristics over a diurnal cycle under submerged condition (SC) and terrestrial condition (TC). Shiga toxin-associated hemolytic-uremic syndrome: combined cytotoxic effects of Shiga toxin, interleukin-1 beta, and tumor necrosis factor alpha on human vascular endothelial cells in vitro. This study describes the Twin-Stage Procedure, in which the cusp angle is used as the main determinant of occlusion because of its reliability.

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Diabetes may negatively affect bone health by unbalancing several pathways: bone formation, bone resorption, collagen formation, inflammatory cytokine, muscular and incretin system, bone marrow adiposity and calcium metabolism. Furthermore, smart carriers have been gradually applied to the delivery system.

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On the basis of these isotope effects, several details of the mechanisms of the enzymatic dehalogenation reactions have been revealed. The major histocompatibility complex-restricted antigen receptor on T hydrochlorothiazide 25 mg vs lasix renal scan cells. Balloon-dilatable b-PAB can be performed safely and prevents PA distortion at later stages.

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Street youth aged 15-19 years in St Petersburg, Russia, have an extraordinarily high HIV seroprevalence. This review surveys the literature on Ti(iv) application in prosthetics bicalutamide long-term side effects and in the development of anticancer therapeutics to gain an insight into soluble Ti(iv) influx in the body and its long-term impact. This study evaluated efficacy and safety of less-frequent ZOL dosing based on bone turnover markers in patients with 1 to 2 years of prior bisphosphonate therapy.

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To compare the effectiveness of constraint induced movement therapy versus motor relearning programme to improve motor function of hemiplegic upper extremity after stroke. The inhibition efficiency of EMMPRIN was validated by real-time fluorescent quantitation polymerase sompraz hp dosage of amoxicillin chain reaction and western blotting.

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Religious Commitment and its Relation to Happiness among Muslim Students: The Educational Level as Moderator. Stenting of the renal artery to improve renal function prior to thoracoabdominal aneurysm repair. Lysophosphatidylcholine (lyso-PC), a biologically active phospholipid, appears to modulate various endothelial cell functions through tyrosine kinase-dependent signaling pathways. Immunoregulatory properties of T-cell lines derived from the systemic and intrathecal compartments: a phenotypic and functional study. To determine the prevalence citopam 20 tablets of pica during pregnancy, maternal hemoglobin levels at delivery, and the association of pica with 2 adverse pregnancy outcomes: low birth weight and preterm birth.

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Eye fundus examination in gestosis patients is an significant guideline for clinical treatment. Since the latter are rather more heavily weighted in the DSM-III criteria for Major Depressive Episode than in typical symptom sum scores, psychosocial variables did not predict DSM-III-defined clinical relapses. In summary, this study replicated the initially reported association of the CRHR1 rs878886 G-allele with cued fear acquisition deficits, albeit with a different pattern of results regarding the interaction with 5-HTT variation. Improving this requires closer collaboration between metal health and hospital healthcare services and training for staff on abacavir sulfate and lamivudine tablets epzicom dosage how to access diagnostic information and recognise common psychological symptoms.

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Virulence and immunogenicity of genetically defined human and porcine isolates of M. Investigative for no-carrier-added 87m,gY production by the proton-induced on 89Y. In the model, the time course of cell segregation follows a power law in accord with experimental observations and dolflam gel para que sirve previous work. The purpose of this study was to characterize pediatric melanoma mortality in the United States and to evaluate trends over time. A longitudinal study of the dental care of adults in the general dental service in Scotland: the first 6 years, 1988-1994.

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The co-evolutionary dynamics that exist in host-parasite interactions sometimes lead to compatibility polymorphisms, the molecular bases of which are rarely investigated. Films were prepared through mixing celcox drug information of chitosan solution and the prepared latex for the first time. The risk of WaveOne fracture is very low when files are singly used by endodontists and residents. Recently, the significance of nosocomial transmission has been challenged by screening on admission studies and whole-genome sequencing, providing evidence for an endogenous source of C.

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Explanatory sequential mixed method design was carried out in Addis Ababa, Ethiopia. 2(nd) biennial meeting of the flemish gynaecological atacor rapido pcb manufacturer oncology group As the majority of nurses today will meet cancer patients during their professional careers, further research is needed in this area. This article sets out to clarify the issue with specific reference to nurse educators who, by the nature of their scope of practice, often do not carry a patient caseload. The polyglutamine tract, beginning at codon 75 in the N-terminal modulatory domain of rat glucocorticoid receptor (rGR), was analyzed in 61 inbred strains and 155 wild caught Rattus norvegicus.

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The best method of management of these injuries is still evolving with considerable amount of work being done in the clinical and biomechanical level. cadista lamotrigine reviews by patients The patients generally seemed to require higher dosing of antidepressants, benzodiazepines, or antipsychotics in order to function normally. The present simulations reveal that the Josephson vortex lattice flow speed is particularly suppressed when the moment of vortex entry matches that of vortex escape.