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Biofenac (Diclofenac)
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Diclofenac

In assessing Biofenac GI toxicity, the effect of the different formulations on the entire GI tract at various times after drug administration must be considered. The liposomal membrane-water partition coefficients of eight ionizable drugs: ibuprofen, Biofenac, 5-phenylvaleric acid, warfarin, propranolol, lidocaine, tetracaine and procaine were determined and the values for neutral and ionized species were found to be in the ranges of approximately 4.5 to 2.4 and 2.6 to 0.8 logarithmic units, respectively.

Other names for this medication:
Diclofenac, Voltaren, Abitren, Aclonac, Afenac, Ainezyl, Aldoron, Algicler, Algifen, Almiral, Anavan, Anodyne, Areston, Arthrex, Arthrotec, Artren, Befol, Berifen, Betaren, Biclopan, Biofenac, Cambia, Campal, Catafast, Cataflam, Clafen, Clofast, Clofenac, Clofenal, Clonac, Cofac, Combaren, Cordralan, Coyenpin, Dedolor, Defanac, Deflam, Deflamat, Deflox, Delimon, Dencorub, Diagesic, Diastone, Diclabeta, Diclac, Diclachexal, Diclax, Diclo, Dicloabak, Diclobene, Dicloberl, Diclobru, Dicloduo, Diclofast, Diclofen, Diclofenaco, Diclofenacum, Dicloflam, Dicloflame, Dicloflex, Diclogen, Diclohexal, Diclomax, Diclomol, Diclon, Diclonex, Diclophlogont, Dicloran, Diclorapid, Diclorarpe, Dicloratio, Dicloreum, Diclosal, Diclosan, Diclotal, Diclotard, Diclovit, Diclowal, Diclox, Dicogel, Difen, Difenac, Difenax, Difene, Diflam, Diflex, Difnal, Diklason, Diklofen, Diklofenak, Dikloron, Diky, Dinac, Dioxaflex, Dirret, Disipan, Dival, Divido, Divoltar, Divon, Dolaren, Dolaut, Dolflam, Dolmina, Dolocordralan, Dolofarmalan, Dolofenac, Dolorex, Dolotren, Dolpasse, Dolvan, Doxtran, Dyclo, Dycon, Dyloject, Dynak, Ecofenac, Eeze, Effekton, Effigel, Eflagen, Emifenac, Emov, Epifenac, Erdon, Feloran, Fenac, Fenactol, Fenadol, Fenalgic, Fenaren, Fender, Fervex, Flamar, Flamatak, Flamydol, Flamygel, Flector, Flexen, Flexin, Flexiplen, Flogozan, Flotac, Fortedol, Galedol, Grofenac, Hifenac, Iglodine, Imanol, Imflac, Inac, Itami, Joflam, Jonac, Kaditic, Kaflam, Kaflan, Kalidren, Katafenac, Kefentech, Klaxon, Klodic, Lertus, Lesflam, Levedad, Linac, Liroken, Lonac, Mafena, Majamil, Masaren, Maxit, Medifen, Merpal, Metaflex, Mobigel, Modifenac, Motifene, Naboal, Naklofen, Nasida, Nediclon, Neodol, Neodolpasse, Neriodin, Neurofenac, Novapirina, Novarin, Ortofen, Ortofena, Panamor, Pennsaid, Polyflam, Primofenac, Profenac, Proflam, Prolertus, Prophenatin, Rapidus, Rapten, Rectos, Refen, Relaxyl, Relova, Remafen, Remethan, Renadinac, Rheumarene, Rheumatac, Rhewlin, Rofenac, Romatim, Rumafen, Salicrem, Sifen, Sofarin, Solaraze, Soludol, Solunac, Subsyde, Supragesic, Surpass, Tabiflex, Taks, Tekodin, Topfans, Tratul, Tromax, Uniclophen, Uniren, Urigon, Valto, Veltex, Vesalion, Viavox, Volcan, Volero, Volfenac, Voltadex, Voltadol, Voltadvance, Voltalin, Voltarenactigo, Voltarol, Volten, Voltenac, Voltex, Voltfast, Voltic, Vostar, Vurdon, Weren, Xedenol, Xedol, Xenid, Zeroflog, Zipsor, Zolterol,

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Prescription topical Biofenac comes as a 1.5% topical solution (liquid) to apply to the knee 4 times a day and as a 2% topical solution (Pennsaid) to apply to the knee 2 times a day. Nonprescription (over the counter) topical Biofenac comes as a 1% gel (Voltaren Arthritis Pain) to apply to up to 2 body areas (e.g., 1 knee and 1 ankle, 2 knees, 1 foot and 1 ankle, or 2 hands) 4 times daily for up to 21 days or as recommended by your doctor. Apply Biofenac gel (Voltaren Arthritis Pain) or topical solution (Pennsaid) at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use topical Biofenac (Pennsaid, Voltaren Arthritis Pain) exactly as directed. Do not use more or less of it or use it more often or for a longer period of time than prescribed by your doctor. Do not apply the gel or topical solution to any area of your body that your doctor did not tell you to treat.

Apply Biofenac gel (Voltaren Arthritis Pain) or topical solution (Pennsaid) to clean, dry skin. Do not apply the medication to skin that is broken, peeling, infected, swollen, or covered with a rash.

Biofenac gel (Voltaren Arthritis Pain) and topical solution (Pennsaid) are only for use on the skin. Be careful not to get the medication in your eyes, nose, or mouth. If you do get the medication in your eyes, rinse your eyes with plenty of water or saline. If your eye(s) are still irritated after one hour, call your doctor.

After you apply Biofenac gel (Voltaren Arthritis Pain) or topical solution (Pennsaid), you should not cover the treated area with any type of dressing or bandage and you should not apply heat to the area. You should not shower or bathe for at least 30 minutes after you apply the topical solution (Pennsaid) and for at least 1 hour after you apply the gel (Voltaren Arthritis Pain). Do not cover the treated area with clothes or gloves for 10 minutes after you apply the gel (Voltaren Arthritis Pain), or until the topical solution (Pennsaid) has dried if you are using the topical solution.

It may take up to 7 days before you feel the full benefit from nonprescription topical Biofenac gel (Voltaren Arthritis Pain). If you do not feel arthritis pain relief from this product after 7 days of use, stop use and contact your doctor.

To use topical Biofenac gel (Voltaren Arthritis Pain), follow these steps:

  1. Before you use a new tube of Biofenac gel (Voltaren Arthritis Pain) for the first time, open the safety seal that covers the tube and then puncture the opening of the tube using the spiked top of the cap. Do not open the seal with scissors or sharp objects.
  2. Place one of the dosing cards from the package on a flat surface so that you can read the print.
  3. Using the lines on the dosing card as a guide, squeeze the correct amount of gel onto the dosing card evenly. Make sure the gel covers the entire area marked for your correct dose depending if it is for the upper (hand, wrist, elbow) or lower (foot, ankle, knee) body. Put the cap back on the tube.
  4. Clean and dry the skin area where you will apply the medication. Do not apply to skin that has any cuts, open wounds, infections or rashes.
  5. Apply the gel to the directed skin areas, using the dosing card to help apply the gel to the skin to up to 2 body areas. Do not apply to more than 2 body areas. Use your hands to gently rub the gel into the skin. Make sure to cover the entire affected area with the gel. Do not apply in same area as any other product.
  6. Hold the end of the dosing card with your fingertips, and rinse and dry the card. Store the dosing card until next use, out of reach of children. Do not share the dosing card with another person.
  7. Wash your hands well after you apply the gel, unless you are treating your hands. If you are treating your hands, do not wash them for at least one hour after you apply the gel.

To use topical Biofenac 1.5 % topical solution, follow these steps:

  1. Clean and dry the skin area where you will apply the medication.
  2. Apply the topical solution to your knee 10 drops at a time. You can do this by dropping the topical solution directly onto the knee or by first dropping it onto the palm of your hand and then spreading it onto the knee.
  3. Use your hand to evenly spread the topical solution around the front, back, and sides of the knee.
  4. Repeat this step until 40 drops of topical solution have been applied and the knee is completely covered with the topical solution.
  5. If your doctor has told you to apply the topical solution to both knees, repeat steps 2 to 4 to apply the medication to your other knee.
  6. Wash and dry your hands well after you apply the topical solution. Avoid skin contact with other people and the treated knee area.

To use topical Biofenac 2% topical solution (Pennsaid), follow these steps:

  1. You will need to prime the pump that contains this medication before you use it for the first time. Remove the cap from the pump and hold the pump upright. Press down the top of the pump four times and catch any medication that comes out on a paper towel or tissue. Throw away the paper towel or tissue in a trash can.
  2. When you are ready to apply your medication, wash your hands well with soap and water.
  3. Hold the pump at an angle and press down the top of the pump to dispense the medication onto your palm. Press down the top a second time to dispense another pump of medication onto your palm.
  4. Use your palm to apply the medication evenly to the front, back, and sides of your knee.
  5. If your doctor told you to apply the medication to both knees, repeat steps 3-4 to apply the medication to your other knee.
  6. Wash your hands well with soap and water as soon as you finish applying the medication.
  7. Replace the cap on your pump and store the pump upright.

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Comparative effects of heparin and the sulfatoid GM1474 on coagulation parameters in plasma and blood from various species. Vesicle fusion is probed by a fluorescence contents-mixing assay. BPD patients showed deficits in planning (short deliberation time in the ToL task) in comparison to BD patients and in comparison to healthy controls.

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Our results indicate that, in skeletal muscle, sarcoglycans have a costameric distribution and all colocalize with each other. Thus, the starfish G protein appeared to be similar to mammalian G proteins at least in terms of its structure and properties of nucleotide binding and the pertussis toxin substrate. Cross-sectional analysis for 1988 exemplified by the Psychiatry Center in the routine health care of Frankfurt The induction of hypothyroidism was associated with a marked increase in myocardial c-myc, c-fos and H-ras mRNAs, changes reversed by 72 h of T3 replacement.

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This study aimed to assess the effects of Bacillus subtilis CU1 consumption on immune stimulation and resistance to common infectious disease (CID) episodes in healthy free-living seniors. It is concluded that nasal arterioles are sensitive to alpha-adrenergic and cholinergic stimulation but not to beta-adrenergic stimulation.

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However, the molecular mechanisms that control chromatin structure, and how the preRC components establish themselves on the chromatin remain to be understood. Pregnenolone is in turn converted to a range of steroid hormones via enzyme casades.

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Native-PAGE showed that Uch-L1 underwent dimerization and oligomerization in gonads, and that the relative level of dimerization/oligomerization decreased during gonadal transformation. A case is presented, in which the delayed diagnosis of diverticulitis resulted in the development of a diverticular mesocolic abscess complicated by hepatic-portal venous gas (HPVG). An increase in the virtual cohesion parameter and a decrease in the excess free energy and the free energy was found with an increase in volume fraction of IPA in the mixed solvent.

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Failure of open radioactive 125iodine implantation to control localized prostate cancer: a study of 41 patients. Statistical analysis of dento-maxillo-facial orthopedic abnormalities underlines their very frequent occurrence. These findings suggest that FIP1L1-PDGFRalpha induces the proliferation of EoL-1 cells through the induction of c-Myc expression via ERK and JNK signaling pathways, but is not involved in the inhibition of differentiation toward mature eosinophils. The 43 -kDa protein was partially purified using a wheat germ agglutinin affinity column. Histamine depolarizes rat medial vestibular nucleus neurons recorded intracellularly in vitro.

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The dispersions of the fifth- and seventh-order nonlinear optical susceptibilities, chi((5))(113333) and chi((7))(11333333) , respectively, of a polydiacetylene film, poly(4-BCMU), are determined through electroabsorption spectroscopy. Accurate determination of the space defined by the physiological contouring of a complete denture (before and after implant surgery) is required during the treatment-planning phase for an implant overdenture.

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However, IGF-I was only detectable in osteoblasts around the bone in the mid and base parts. A historical and chronological literature review of the therapies applied since 1910.

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In a previous paper, we characterized several single-point mutants of the C-terminal helix (CTH) that alter global stability of EcTRX. Gene frequencies of 4 STR loci in Tibetan population of Yunnan province We further replicate our findings both in an expanded male cohort and an independent female study group.

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Twenty-eight cats had non-regenerative IMHA (24 had erythroid hyperplasia and 4 had erythroid maturation arrest) and 29 had PRCA. Cytopathologic examination is of considerable aid in the diagnosis of OHC since cytopathologic preparations highlight the characteristic cell pleomorphism.

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Dysphagia in the elderly: preliminary evidence of prevalence, risk factors, and socioemotional effects. Without rejecting this view, we call for the implementation of sustainable solutions to deal with the long term ART challenges. The modern management of abdominal stab wounds remains controversial and subject to continued reappraisal.

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Determinants of the delegation of healthcare aboard ships with women assigned. To ensure that these survivors maximize the productivity of their lives, neurologists must not only optimize medical management but also recognize that impairments in cognition and mood may be remediable barriers to long-term functional independence. We conclude that glutathionylation of beta-actin may occur via spontaneous oxidation of a cysteinyl residue to a sulfenic acid that readily reacts with GSH to form a mixed disulfide. Carbonic anhydrase from both the cytoplasmic and membrane fractions of the forebrains of rats was characterized with respect to enzymatic activity, immunoreactivity, and in vitro biosynthesis. During 10 years, 867 patients in whom the same surgical team had performed coronary bypass were followed up regularly without any of them being lost sight of.

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We used a narrative synthesis to describe the effectiveness of the interventions on various outcomes, because of significant heterogeneity among studies. Early and late arterial healing response to catheter-induced laser, thermal, and mechanical wall damage in the rabbit. Many studies have demonstrated that CSCs play important roles in tumor growth, spread and metastatic relapse after treatment, and are closely related to the prognosis of patients. As(V) was completely reduced to As(III) in spent granular ferric oxide (GFO) under 2-year incubation. Wild type and calpastatin overexpressing (CST1) cells were neuronally differentiated and apoptosis-induced with staurosporine (0.1-1.0 microm).

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In addition, patients with total IgA deficiency showed a significant increase in infection-related rhinosinusitis, tonsillitis and conjunctivitis, when compared with patients with partial IgA deficiency. Interestingly, costimulation by thrombin plus collagen together with each of the other agonists increased the phosphatidylserine exposure induced by strong agonists. Similarily, p120cas, the Arm domain containing src substrate, also binds to cadherins and becomes tyrosine phosphorylated in response to a variety of stimuli. The theory of functional systems: general postulates and principles of dynamic organization (dedicated to the Anokhin Centenary). This setup was applied to a broad-area laser diode operating on the D(1) line of the cesium atom at 894 nm, yielding single-mode emission.

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fermentans is an organism capable of infecting humans and in an early report has been discussed as a causative agent for rheumatoid arthritis. Autosomal recessive cerebellar ataxia caused by a homozygous mutation in PMPCA.

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Cell count, PRL expression, Smad and ERK phosphorylation, cyclooxygenase (COX)-2 expression, and prostaglandin E(2) (PGE(2)) release. Comparison of human tumor cells (Hep 2) and rat liver for the detection of antinuclear antibodies by indirect immunofluorescence Diagnoses included congenital amputations, phocomelia, radial agenesis, traumatic amputations, and infected fracture with bone loss. The purpose of this study was to undertake a three-dimensional analysis of the microvascular network of the glandular body and the excretory ducts system of the dog parotid gland using microcorrosive resin casting technique and examined under scanning electron microscope. To determine the active site of exfoliative toxin B (sETB) of Staphylococcus aureus, the etb gene was cloned from an S.

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Sudden changes in periodicity or velocity resulted in inappropriate eye movements correlated highly with previous stimulus cycles. Multivariate analysis proved pleural effusion to be one of the significant prognostic factors, especially in patients with poor PS. In xenograft tumors generated by injection of wild-type mice with lung adenocarcinoma cells alone or in combination with CAFs, the total concentration of collagen cross-links was the same in tumors generated with or without CAFs, but coinjected tumors had higher hydroxylysine aldehyde-derived collagen cross-links (HLCC) and lower lysine-aldehyde-derived collagen cross-links (LCCs). The guanine residues located at positions 37, 41, 56, 66, 75 and 89 were modified.

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When the cells were treated with damnacanthal prior to ultraviolet irradiation, DNA fragmentation was more pronounced as compared to the case of ultraviolet irradiation alone. In this presentation, two patients with affective disorder and dementia are described. The interplay between nanoparticle characteristics and release mechanisms can be captured using computational models. This article establishes a comprehensive review of all the different methods proposed by the literature concerning augmented reality in intra-abdominal minimally invasive surgery (also known as laparoscopic surgery). But the precise role of heme in oxygen sensing and the transcriptional regulation of oxygen-responsive genes is presently unclear.

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Undisturbed soil cores (100 cm) were collected from the topsoil of two agricultural sites in Denmark with soils of sandy loam texture. Conversely, the alternative pathway (AP) is actively down-regulated on host tissue. These data showed that the T cells that formed clusters were mainly CD4 positive-2H4 positive cells.

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Large private, not-for-profit, academic medical center in San Francisco, California, 2004-2006. The only advantage of reduced dietary protein in this study was a reduction in blood urea nitrogen (BUN).

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Proliferation was augmented 40-100 fold by inclusion of IL-2 in cultures. The other three patients had undergone hematopoietic stem cell transplantation (HSCT). To determine if suppressor cells for isotypes other than IgE are induced by R-BSA, cell transfers were performed.

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Further research is necessary to validate the signs and symptoms found in this study. The occupational disease reporting system in China still does not have full function in monitoring and early warning. III: synthesis, antiviral and pharmacokinetic profiles of symmetrical heteroaryl carboxamides. Transition from third- to fourth-stage larvae (L4) started as early as 48 h after transfer to vertebrate conditions in vivo in surrogate hosts and in vitro.

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The highest number of physically inactive subjects was found in men and women in the 35-year age group. The serum of 29 out of 37 egrets from the same colony contained neutralizing antibodies to the virus. We performed a retrospective cohort study in 414 patients with infrarenal AAA who visited The University of Tokyo Hospital.

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Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease. pseudomallei mutants, including rpoS, ppk, and bpsI isolates, were determined. Oligopeptide substrates representing the naturally occurring cleavage sites in HTLV-1 were good substrates of the HTLV-1 proteinase.

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The effect of a drug and supply cost feedback system on the use of intraoperative resources by anesthesiologists. Therefore, IL-10 can directly inhibit STAT-dependent early response gene expression induced by both IFNalpha and IFNgamma in monocytes by suppressing the tyrosine phosphorylation of STAT1. Preparation of monoclonal antibodies by intrasplenic immunization of mice with urine circulating antigen from patients infected with Schistosoma japonicum

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CXCL10 declined during the follow-up, while CCL2 remained unmodified, suggesting that the disease progresses from the early Th1 inflammatory condition to the advanced Th2-like stage. An abbreviated version of the negative symptom scale was especially effective in separating groups. Antigen distribution was heterogenous and present in BCC, epidermis, hair follicles, dermal mononuclear cells, and extracellular matrix. A herd on Svalbard Island, Scandinavia, is an exception, with relatively few alleles and low heterozygosity. The surprising occurrence of MBL-initiated lysis in the absence of calcium contrasts with the calcium requirement for C1q-initiated activation of C4 and C2.

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These results indicate that the human GC culture system is more complex than is often assumed, and methods that remove a majority of these white blood cells are presented. The relative biological values of the proteins in cereal grains. Cells within the vast majority of human tissues communicate directly through clustered arrays of intercellular channels called gap junctions. Differences and overlap in self-reported symptoms of bipolar disorder and borderline personality disorder. Dynamics of the X-sex chromatin in the buccal epithelial cells of pregnant women with rhesus-negative blood

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Chronic use of diazepam in primary healthcare centers: user profile and usage pattern. Significant improvements were found after surgery in clinical and functional vision and perceived visual disability. The main efficacy end points were the safety of topical imiquimod and the overall clinical response in patients evaluated on the basis of modified AIDS Clinical Trials Group criteria at 36 weeks.

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The relationship between neuropsychological measures and self-care skills in patients with cerebrovascular lesions. Whether this is due to limited access to healthcare for the medical problems or better coordination between medical and mental health providers, which reduces duplicated medical procedures or visits, requires future investigation. Randomized controlled trials (RCTs) were analyzed to compare therapy combining SSRIs and electroacupuncture to SSRI therapy alone. Sensitivity to transformation by ether is limited in time to the interval between the passing of the two wavefronts. Our observations are explained in terms of bulk excursions that introduce jumps with a heavy-tail distribution.

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Genomic DNA was evaluated for RHD alleles with multiplex RHD exon polymerase chain reaction (PCR), weak D PCR-restriction fragment length polymorphism, and RHD exon 5 and 7 sequence analyses. Assessment of biodegradative potential and activity in contaminated sites: molecular approaches to environmental monitoring. First, the disruption of the Ter macrodomain with replication forks merging far from the normal replichore junction provoked chromosome segregation defects.

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Polyphosphate administration may be an alternative approach to prevent anastomotic leak induced by collagenolytic bacteria with the advantage of preserving the intestinal microbiome and its colonization resistance. A significant proportion of their DNA migrated during agarose gel electrophoresis as nicked DNA. General NF-kappaB activity and specific NF-kappaB suppression of bone morphogenetic protein-4 expression were not altered in fibrodysplasia ossificans progressiva. Subsequent host-mediated silencing, however, necessitates the expression of EBNA-1 from the EBNA-1-specific promoter Qp to ensure against genome loss during cell division, including EBV-associated malignancy. Lipid profile in men and women with different levels of sports participation and physical activity.

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