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Calutide (Bicalutamide)

Calutide is an oral medication that is used for treating cancer of the prostate. It belongs to a class of drugs called anti-androgens which includes flutamide (Eulexin) and nilutamide (Nilandron). Androgens (an example of which is testosterone) are hormones that are produced and released by the adrenal glands. They are responsible for supporting (stimulating) tissues that primarily are thought of as male, for example, the male prostate gland. Male traits that also are influenced by androgens include facial and body hair, and small breasts. Anti-androgens prevent the action of androgens by blocking the receptors for androgens on the cells of tissues, for example, the cells of the prostate gland. In addition to normal prostate cells, androgens also have been shown to stimulate the growth of cancer cells within the prostate. Calutide is thought to prevent the growth of prostate cancer by blocking the effects of androgens on the cancer cells. Calutide was approved by the FDA in 1995.

Other names for this medication:
Bicalutamide, Casodex, Bicalox, Bicalutamida, Bicusan, Bidrostat, Caluran, Calutide, Calutol, Capro, Cosudex, Imda, Lutamidal, Probic, Zolacos,

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Calutide is used with another medication (gonadotropin-releasing hormone (GnRH) agonists; such as leuprolide or goserelin) to treat metastatic prostate cancer (cancer that started in the prostate and has spread to other parts of the body). Calutide is in a class of medications called nonsteroidal antiandrogens. It works by blocking the effect of androgen (a male hormone), to stop the growth and spread of cancer cells.

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Cadmium accumulation and its phytotoxicity in Potamogeton pectinatus L. Biopsy guided by ultrasonography leads to histological diagnosis. Bacterial diversity in medication-related osteonecrosis of the jaw. Physicians who experience more burnout are less likely to identify with medicine as a calling. Microrandomized trials enable causal modeling of proximal effects of the randomized intervention components and assessment of time-varying moderation of those effects.

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Tumor enzymes and prognosis in transitional cell carcinoma of the bladder: prediction of risk of progression in patients with superficial disease. Exacerbations of chronic obstructive pulmonary disease (COPD) are usually treated with bronchodilator therapy, glucocorticoids and antibiotics.

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with Rhizobium leguminosarum and of the fodder galega Galega orientalis Lam. These results are discussed in view of chromatin structure and function.Images

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Minor experience still exists in our country with regard to the use of valve homografts in cardiac surgery. The presence of alpha(1)-adrenoceptors on the endothelium suggests that these receptors may participate in regenerative phenomena by regulating the responses of endothelial cells involved in neo-angiogenesis. The increase in non-communicable disease (NCD) is becoming a global health problem and there is an increasing need for primary care doctors to look after these patients although whether family doctors are adequately trained and prepared is unknown. To test the feasibility of MR-guided coil embolization with passive visualization in an animal model.

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Since it is known that pre-eclampsia is associated with increased sympathetic activity, administration of an alpha 1 adrenoceptor antagonist provides a reasonable therapeutic basis. Increased sympathetic activity can contribute to sustained hypertension not only because of its hemodynamic effects (increased cardiac output and vascular resistance), but also by altering renal and water handling by the kidney, and by inducing cardiac and vascular remodeling. To evaluate the efficacy of atorvastatin, when not administered everyday, on LDL-cholesterol (LDL-C) levels, and also to evaluate cost reduction. To explore the possibility of microencapsulation of chondrocytes in cartilage tissue engineering, immortalized manibular condylar chondrocytes (IMCCs) were microencapsuled by Alginate-polylysine-alginate (APA) method, according to air pressure shearing model. Compare nutritional status of 57 South African mothers of children with fetal alcohol spectrum disorders (FASD) with 148 mothers of controls.

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The author describes the principles of studying the urine by using millipore technique searching for neoplastic cells. In the case of a 15-year-old girl who underwent partial extirpation of craniopharyngioma, favorable endocrine effects were obtained by pulsatile gonadotropin-releasing hormone treatment.

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Meiotic drive by the Y-linked D gene in Aedes aegypti (L.) (Diptera: Culicidae) is associated with disruption of spermiogenesis, leading to premature senescence of spermatozoa. We evaluated, in a prospective case-control study, consecutive patients with IIM who were referred to our center and ascertained without regard to family history or known risk factors for autoimmunity, and all available family members. A study of nonbacterial agents of acute lower respiratory tract infection in Thai children. Of the 220 officers currently (as of April 1990) detailed to EPA, most are in the engineer category.

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Although DY131 alone did not change any gene, treatment of DY131 in the presence of Esrrb altered 1161 mRNAs. The authors describe a case of a female patient with a septic shock of unclear origin. In contrast, infusion into the dorsal or medial portion of the LHA tended to produce a small decrease with a return to baseline within approximately 60 min after the end of the infusion. In spite of this suppression, the increase in uterine activity was similar to the group which had not received indomethacin. Methods for other mycotoxins such as ochratoxin, patulin, and the trichothecenes are also included.

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Kernel machine based association tests (KAT) have been increasingly used in testing the association between an outcome and a set of biological measurements due to its power to combine multiple weak signals of complex relationship with the outcome through the specification of a relevant kernel. Periosteal bone apposition was observed in the bones: and genu valgum of the limbs.

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The results show that the specific immunocompetent cells were predominantly found in the upper and middle part of the periodontal pocket. A hospital database search in which four patient groups including those with a diagnosis of osteoporosis-related vertebral fracture, osteoporosis, osteopenia, or vitamin D deficiency and a control group were evaluated for chart-documented height loss over an average 3 1/2 to 4-year time period. We wanted to investigate if priming of a subsequent specific IgE response could be achieved by dosing newborn rats orally with ovalbumin and if this method could be used in an animal model for food allergy.

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Diabetes mellitus (DM) in dogs is a common endocrinopathy with a complex genetic architecture. We now report the cloning and sequencing of the cDNA coding for the Drosophila IDE (dIDE). Extracellular spikes of a single vestibular neuron were recorded in decerebrated cats. Here, we describe the characteristics of this new animal model in detail. Their eGFR was calculated using the MDRD, CKD-EPI, their respective modified equations for Chinese, and the diabetes specific CKD-EPI Chinese T2DM equations.

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The ATP-gated ionotropic P2X7 receptor (P2X7R) modulates glial activation, cytokine production and neurotransmitter release following brain injury. It then presents detailed comparisons between the S-system representation and other variants within Biochemical Systems Theory. The other disposition rate constants are readily obtained without intravenous data. This study investigated if obstructive sleep apnea syndrome (OSAS) may be associated with higher activity in different frequency bands of the EEG during a sustained wakefulness paradigm.

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