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Abalam (Abacavir)

Abalam is a guanosine nucleoside analog with potent activity against HIV. However, in the premarketing phase of drug development, multiple reports emerged of a hypersensitivity syndrome associated with Abalam, which led to significant morbidity. Rare reports of mortality were associated with failure to recognize this clinical syndrome as drug hypersensitivity.

Other names for this medication:
Abacavir, Abalam, Epzicom, Kivexa, Abamune, Virol, Ziagen,

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This product contains 2 drugs: Abalam and lamivudine. It is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Abalam and lamivudine both belong to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs). Abalam/lamivudine is not a cure for HIV infection. To decrease your risk of spreading HIV disease to others, do all of the following: (1) continue to take all HIV medications exactly as prescribed by your doctor, (2) always use an effective barrier method (latex or polyurethane condoms/dental dams) during all sexual activity, and (3) do not share personal items (such as needles/syringes, toothbrushes, and razors) that may have contacted blood or other body fluids. Consult your doctor or pharmacist for more details. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This product may also be used in combination with other HIV medications to reduce the risk of getting HIV infection after contact with the virus. Consult your doctor for more details.

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In Triops and Nebalia, development of limb branches is not tightly coupled with Dll expression: in some cases, branches can arise prior to Dll expression and in others, certain branches never express Dll. Binding involves residues of actin also recognised by myosin subfragment 1.

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The aim of this study was to evaluate the effect of cardiac shock wave therapy (CSWT) on microvolt T wave alternans (MTWA) in patients with coronary artery disease (CAD). Once the patient is placed on the transplant wait list after undergoing an initial extensive evaluation, continued surveillance is required. An integrated microfluidic system for diagnosis of the resistance of Helicobacter pylori to quinolone-based antibiotics. In the present study, these genes were inserted into an inducible eukaryotic expression vector, pMSG, and transfected into NIH 3T3 mouse fibroblasts. While high degrees of resistance to MPA, DEX and E2 were achieved, cells remained anti-oestrogen-sensitive after prolonged treatment with 4 microM tamoxifen (TAM) or the anti-oestrogen LY 117018 (LY).

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The temperature-composition phase diagrams have been established. Treatment with either drug was neither interrupted nor discontinued because of toxicity. No significant differences were found between blood pressure reductions in 5 patients with elevated PRA, 5 patients with slightly elevated PRA, and 7 patients with normal or low PRA.

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The developmental disabilities questions in the 2014 National Health Interview Survey (NHIS) were changed from previous years, including question reordering and a new approach to asking about autism spectrum disorder (ASD). Diabetic patients have been suggested to have a hypercoagulable state. Generalized Kubelka-Munk approximation for multiple scattering of polarized light.

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Observation of audio-frequency edge magnetoplasmons in the classical two-dimensional electron gas. The permeable membrane-like edge of the ring is composed of adenine filaments glued together by silver nanoparticles. The primary endpoint was independently reviewed overall response in the full analysis set.

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The hydration effects and mechanisms were explored by examining the dynamic mechanical properties and thermal behaviors. stones received 1,800 to 3,200 shock waves by an electromagnetic lithotriptor. Mycetoma is a chronic, granulomatous, subcutaneous, inflammatory disease caused by true fungi (eumycetoma) or filamentous bacteria (actinomycetoma).

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The activity of liver and adipose tissue is very sensitive to changes of diet. The diagnosis was suspected on clinical grounds and verified by ultrasonography, computed tomography or angiography or a combination thereof. The relations between the cytotoxic adherent cells (CAC) and the peroxidase positive adherent cells (PPAC) which appeared after i.p. Two self-report measures, DASS-21 and Brief Symptom Inventory (BSI), assessed Depression, Anxiety and Stress. There were 29 CDH patients with PH including 16 males and 13 females.

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Compartmentalization of acetylcholine receptor gene expression during development of the neuromuscular junction. Degree of anticoagulation, but not warfarin use itself, predicts adverse outcomes after traumatic brain injury in elderly trauma patients. The patients now receive a parenteral solution containing biotin and have shown no recurrence of alopecia.

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The ratio of factor VIII coagulant activity (VIIIC) or antigen (VIIICAg) to that of factor VIII related antigen (VIIIRAg) was measured in 15 normals, 21 obligatory and 23 possible carriers of hemophilia. The response to the liganded thyroid hormone receptor (TR) was mediated by an unusual thyroid hormone response element located between -1000 and -987 relative to the transcription start site. Furthermore, it moderated the relationship between level of home damage and personal recovery as well as the relationship between home damage and post-traumatic stress disorder (PTSD), with stronger effects for those with increased levels of home damage. Effective agents targeting these molecular abnormalities have been developed and widely tested in preclinical studies of HCC cell lines or xenograft models. Here we discuss data obtained by this powerful experimental approach by which to study several issues of the cerebellar ontogenesis.

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This study examined views of first year Foundation doctors (F1s) regarding how prepared they felt by their undergraduate medical education for skills required during the first Foundation training year in relation to their type of training. The diagnosis of an adrenocortical adenoma may be established by CT in most patients and by MRI in an additional number. Differential effect of acute baroreceptor unloading on cardiac and systemic sympathetic tone in congestive heart failure. Our main interests concern the structure of muscle and muscular components. Laboratory research on their biology have been hampered so far by the absence of cell lines representative of CUPs.

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The concentration of gastrin releasing peptide-like immunoreactive substance (GRP-IS) was measured by enzyme immunoassay (EIA) in rat mammary glands during pregnancy and after delivery. Of these, two focused on Native Hawaiians and/or other Pacific Islanders and three focused on overall youths in Hawaii. Besides, a GLT value of 180 mg/dl or higher proves the diagnostic test unnecessary as these patients are associated with unfavorable perinatal and fetal outcomes. In the improved 2-dimensional display, distance-weighted and volume-weighted polar maps are used that appear to significantly improve the representation of defect location and defect extent, respectively.(ABSTRACT TRUNCATED AT 250 WORDS) The implicit water model uses the finite difference Poisson (FDP) model with the smooth permittivity method implemented in the OpenEye ZAP libraries.

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Perfect wave-number selection and drifting patterns in ramped Taylor vortex flow. We used three hamster cell lines defective in HR either by overexpression of a RAD51 dominant-negative form, or by a defect in the RAD51 paralogue XRCC2 or the breast tumor suppressor BRCA2. (1) Ipsilateral hemiataxia following dorsolateral medullary infarctions results from a lesion of the dorsal spinocerebellar tract and the inferior cerebellar peduncle conveying afferent information from the ipsilateral arm and leg. After transfection of pUTdelta1.7 into HuH7 cells, antigenomic HDV RNA was produced, processed and could enter into the replicative cycle of HDV. Further studies are needed to definitely connect these increase morbidity figures to increase prevalenc of the C282Y mutated HFE-gene and elevated serum iron indices.

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Infusion of tPA into tPA-/- mice restored sensitivity to kainate-mediated neurotoxicity and activation of microglia. It may, therefore, be a potential nutritional supplement in chemotherapy. Its function as a phagocytic receptor for iC3b-coated particles has been well characterized. The aim of the current study was to explore perceptions regarding causes, consequences, control, concerns and time course of obesity of centrally obese adults, with and without an elevated cardiometabolic risk and with or without weight loss, 3 years after screening for metabolic syndrome, and to compare these perceptions. The underlying regulatory processes which determine the nature of long-term immunological memory against these antigens appear to involve a combination of classical high zone and low zone tolerance mechanisms.

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Volume-time curves were derived and the results compared to those from manual segmentation. Increased levels of VEGF and angiogenic markers are associated with poor outcome in endometrioid endometrial cancer patients. Blockage of caspase-1 activation ameliorates bone marrow inflammation in mice after hematopoietic stem cell transplantation. Sequence analysis predicted a conserved binding site for Pax3 within the Wnt1 promoter region.

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Activated endothelial cells are a potent source of interleukin-6 and its persistence in the circulation may be taken as evidence of continuing disease activity. Despite the overall success of total knee arthroplasty (TKA), a relatively large proportion of patients remain dissatisfied with the outcome.

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The extracted dye was measured by spectrophotometry and compared with the total dye recovered from control cells. Males with or without a history of infertility providing semen samples at a university central laboratory. Association between a large plasmid and 15- to 17-kilodalton antigens in virulent Rhodococcus equi.

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Genetic alterations of target chromosomes such as aneuploidy in Chinese biliary cancer cell lines and tissues were measured using a UroVysion kit. We asked whether cochleovestibular anomalies coexist in individuals with cholesteatoma. A stepped care approach may improve outcomes and needs rigorous evaluation.

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The altered genes are involved in cellular processes related to the development of cervical carcinoma, such as adhesion, angiogenesis, apoptosis, differentiation, cell cycle, proliferation, transcription and protein translation. An interspecific hybrid as a tool to study phylogenetic relationships in plants using the GISH technique. Both polyclonal and monoclonal antibodies could be used individually in an indirect enzyme-linked immunosorbent assay (ELISA) to measure specific anti-BSA Ig in HSB serum. Larger studies are required to confirm these results, but findings are promising for the treatment of large numbers of HCV-infected patients who may require subsequent immunosuppressive or immunomodulating therapies.

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Medical Findings and Toxicological Analysis in Infant Death by Balloon Gas Asphyxia: A Case Report. Molecular cloning, characterization and expression analysis of caspase-3 from the oriental river prawn, Macrobrachium nipponense when exposed to acute hypoxia and reoxygenation. In light of the above, a clinical study was designed to evaluate the bioequivalence of two fixed dose combination (FDC) products of two manufacturers containing nitazoxanide 500 mg and ofloxacin 200 mg in healthy Indian male volunteers. Fifty-four research papers generated 304 study findings that were aggregated into nine categories. Evidence for increased calpain activity has been described in the hippocampus of rodent models of temporal lobe epilepsy.

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One transcript, expressed in the precursor but downregulated in the tumor cells, was cloned and identified as the murine calcium channel mtrp6. We hypothesized that participants with higher obsessive compulsive (OC) features would set their decision thresholds higher and thus make more cautious decisions.

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A systematic review on the outcome of surgical vs non-surgical procedure for the retreatment of periapical lesions. In contrast, antibodies to SSF were absent in healthy control sera. TGFBI gene transcript is transforming growth factor-beta1-responsive and cell density-dependent in a human corneal epithelial cell line. Should anxiety and insomnia influence antidepressant selection: a randomized comparison of fluoxetine and imipramine.

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Indications for surgical treatment of varicocele in the prepubertal age The authors present gastroschisis which occurred in a surviving fetus after the co-twin demise in a monochorionic pregnancy. Group Psychotherapy with Transgender and Gender Nonconforming Adults: Evidence-Based Practice Applications.

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Work experience in shaping a healthy life style in the industrial enterprise The shape of a concentration-response curve (CRC) is determined by underlying equilibrium constants for agonist binding and receptor conformational change. Patients were excluded if they had undergone previous cardiac surgery or if they lacked co-operation.

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All over the lower urinary tract strong to weak ChAT-, CGRP-, SP- and NPY-immunoreactivity was detected in intramural ganglia, in peripheral nerve bundles and around blood vessels. Evaluation of changes in hemoglobin levels associated with ABO-incompatible plasma in apheresis platelets. This study evaluates the results of a multicenter experience with dynamic muscle plasty in the treatment of fecal incontinence and total anal reconstruction.

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